Multiple Sclerosis (MS) is a highly disabling neurological disease characterized by inflammation, neuronal damage, and demyelination.Vision impairment is one of the major clinical features of MS.Previous studies from our lab have shown that MDL 72527, a pharmacological inhibitor of spermine oxidase (SMOX), is protective against neurodegeneration an
University Transformation Model: Theory and Practice
This article considers the Lip Balms identification of the VUCA-world influence as a modern reality on the transformation of University on the example of Norilsk State Industrial Institute, its internal development space.The research relies on various methods: case-method, foresight, design method, depth interviews with the most important stakehold
Restricted-range fishes and the conservation of Brazilian freshwaters.
BACKGROUND: Freshwaters are the most threatened ecosystems on earth.Although recent assessments provide data on global priority regions for freshwater conservation, local scale priorities remain unknown.Refining the scale of global biodiversity assessments (both at terrestrial and freshwater realms) and translating these into conservation prioritie
Robustifying and simplifying high-dimensional regression with applications to yearly stock return and telematics data
Abstract The availability of many variables with predictive power Fly Rugs makes their selection in a regression context difficult.This study considers robust and understandable low-dimensional estimators as building blocks to improve overall predictive power by optimally combining these building blocks.Our new algorithm is based on generalized cro